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Biological Implications of Circadian Disruption

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Biological Implications of Circadian Disruption

Biological Implications of Circadian Disruption

A Modern Health Challenge
Laura K. Fonken , University of Texas, Austin
Randy J. Nelson , West Virginia University
October 2023
Available
Hardback
9781316512081

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    Description

    Life on earth has evolved under a consistent cycle of light and darkness caused by the earth's rotation around its axis. This has led to a 24-hour circadian system in most organisms, ranging all the way from fungi to humans. With the advent of electric light in the 19th century, cycles of light and darkness have drastically changed. Shift workers and others exposed to high levels of light at night are at increased risk of health problems, including metabolic syndrome, depression, sleep disorders, dementia, heart disease, and cancer. This book will describe how the circadian system regulates physiology and behavior and consider the important health repercussions of chronic disruption of the circadian system in our increasingly lit world. The research summarized here will interest students in psychology, biology, neuroscience, immunology, medicine, and ecology.

    • Provides an interdisciplinary approach to understanding the circadian system and how it regulates cellular, tissue, and whole-body level physiology and behavior
    • Chapters provide an accessible description of the basic regulation of different body systems
    • Includes perspectives from basic research models, clinical work, and epidemiological research
    • Provides information on areas for intervention such as minimizing environmental light pollution

    Product details

    October 2023
    Hardback
    9781316512081
    360 pages
    260 × 185 × 27 mm
    0.95kg
    Available

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    Contents

    Table of Contents

    • 1. Introduction to circadian rhythms Laura K. Fonken and Randy J. Nelson
    • 2. Central clock dynamics: daily timekeeping, photic processing, and photoperiodic encoding by the suprachiasmatic nucleus Deborah A. M. Joye, Robert Wheeler and Jennifer A. Evans
    • 3. Melatonin, light, and the circadian system Margarita L. Dubocovich
    • 4. Disrupted circadian rhythms, stress, and allostatic load Ilia N. Karatsoreos
    • 5. Disrupted circadian rhythms and mental health Anthony Rosenthal and Tara A. LeGates
    • 6. Circadian rhythms and cognitive functioning Jacob S. Moeller and Lance J. Kriegsfeld
    • 7. Circadian rhythm disruption in aging and Alzheimer's disease Marilyn J. Duncan
    • 8. Circadian rhythms regulate neuroinflammation after traumatic brain injury and spinal cord injury Andrew D. Gaudet and Emily K. Greenough
    • 9. Disrupted circadian rhythms and neuroendocrine function in fertility Alexandra M. Yaw, Brooke M. DeVries and Hanne M. Hoffmann
    • 10. Disrupted circadian rhythms and metabolic function Deanna M. Arble
    • 11. Disrupted circadian rhythms, time restricted feeding, and blood pressure regulation Zhenheng Guo, Tianfei Hou and Ming C. Gong
    • 12. Disrupted circadian rhythms and immune function Louise M. Ince, Devin Simpkins and Julie E. Gibbs
    • 13. Circadian rhythms and cardiac function Leandro C. Brito, Saurabh S. Thosar, and Matthew P. Butler
    • 14. Disrupted circadian rhythms and cancer Baharan Fekry and Kristin Eckel-Mahan
    • 15. Light effects across species in nature: a focus on solutions Kevin J. Gaston and Johanna H. Meijer
    • 16. Measurement and analysis of exposure to light at night in epidemiology Xiaozhe Yin and Travis Longcore.
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      Contributors

    • Laura K. Fonken, Randy J. Nelson, Deborah A. M. Joye, Robert Wheeler, Jennifer A. Evans, Margarita L. Dubocovich, Ilia N. Karatsoreos, Anthony Rosenthal, Tara A. LeGates, Jacob S. Moeller, Lance J. Kriegsfeld, Marilyn J. Duncan, Andrew D. Gaudet, Emily K. Greenough, Alexandra M. Yaw, Brooke M. DeVries, Hanne M. Hoffmann, Deanna M. Arble, Zhenheng Guo, Tianfei Hou, Ming C. Gong, Louise M. Ince, Devin Simpkins, Julie E. Gibbs, Leandro C. Brito, Saurabh S. Thosar, Matthew P. Butler, Baharan Fekry, Kristin Eckel-Mahan, Kevin J. Gaston, Johanna H. Meijer, Xiaozhe Yin, Travis Longcore

      • Editors
    • Laura K. Fonken , University of Texas, Austin

      Dr. Laura K. Fonken is an Assistant Professor at the University of Texas Austin, USA. She earned her BS in Biology and Psychology from Syracuse University before completing a Ph.D. in Neuroscience at The Ohio State University in 2013. She has published over sixty academic papers and reviews, twenty of which are focused on circadian regulation of physiology and behavior. She was awarded the Society for Behavioral Neuroendocrinology Frank A. Beach Early Career Award and the Texas Society for Circadian Biology and Medicine Ron Konopka Junior Faculty Award.

    • Randy J. Nelson , West Virginia University

      Dr. Randy J. Nelson is Professor and Inaugural Chair of the Department of Neuroscience at West Virginia University, USA. He holds the Hazel Ruby McQuain Chair for Neurological Research. He also directs the WVU Center for Foundational Neuroscience Research and Education, and the foundational science program for the Rockefeller Neuroscience Institute. He earned his AB and MA degrees in Psychology from the University of California at Berkeley, USA, before completing a Ph.D. in Psychology and a Ph.D. in Endocrinology. He has authored and edited ten books, including An Introduction to Behavioral Endocrinology (6th edition, 2022).

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